As they beat Liverpool 2-0 to go level on points with the champions, Everton recorded their first Premier League win at Anfield since 1999.
After just three minutes, Richarlison put Everton ahead, latching on to James Rodriguez’s through-ball before firing past Alisson.
Before Alisson denied Seamus Coleman’s header, Jordan Henderson’s volley forced a fingertip save from Jordan Pickford. Henderson then limped off in defence to deepen Liverpool’s injury woes.
With Pickford thwarting Sadio Mane and then Mohamed Salah when through on goal, Liverpool started the second half brightly.
Jurgen Klopp’s first derby defeat and Liverpool’s fourth home loss in a row were confirmed seven minutes from time.
After fellow substitute Dominic-Calvert Lewin had been fouled by Trent Alexander-Arnold, Gylfi Sigurdsson converted a penalty.
On 40 points, Everton is seventh, below Liverpool on goal difference but having played less of a match.